Combination immunotherapy of nivolumab plus ipilimumab in a lung cancer patient with Werner syndrome; a case report
Werner syndrome (WS) is a rare progressive Brackets disorder that is characterized by premature aging of all organs.Malignancy is a frequent complication of WS, however, lung cancer patients with WS are much rare.In patients with WS, the treatment for malignancy is often limited due to other complications of severe skin ulcer, diabetes mellitus and